25% need the CA125 Ovarian Cancer Blood Test?
This Marker is present during embryonic development at the level of the coelomic epithelium and in the amniotic fluid. It is also found in a high percentage of HPV tumours of epithelial origin and can be detected by a test in the serum of women with invasive primary disease. Therefore, conditions that can cause an increase include many that aren’t cancerous, such as menstruation and uterine fibroids. Specific cancers, including ovarian, endometrial, peritoneal, and fallopian tube types, may also cause increased levels.
Why choose our CA125 Levels Exam?
The Laboratory that processes the samples uses CE-certified special purpose extremely high tech instruments and robotic machines that are from the largest Medical suppliers in the world
- We have Technology that is leading.
- We have reasonable Prices due to Batch Processing each 1-7 days.
- Support is actioned each day by Medical Laboratory People not just anyone that can do customer service.
- Pre-Paid Royal Mail Tracked 24/48, Return to Lab Label included.
- Result Certificate Issued by Confidential Email (No SMS)
- Jump the queue option for £50
- WhatsApp Support with Laboratory Staff
- Prescription Bundle Referral for £60
Whats Included in the CA125 Kit?
Self Finger Prick Tube Kit
- BD Microtainer Industry Standard*
- Sample return clear safety bag.
- Absorbing Pad
- Return UN3373 Labelled Bag.
- Return label option at the checkout.
- Instructions for use.
- Pre-Return Online Sample Registration
- Free Replacement Kit if loss or Damage
- Plain White package for privacy and discretion from neighbours
- Cost effective Standard kit with Upgrade Kit Option for £50
- Patient Request Comments Box (read by the Laboratory Staff processing your sample for better quality and communication)
*During shortages we may substitute CE approved Alternative.
Register your Sample Tube from your Kit here in your Account dashboard.
Steps to order the CA125 Tumour Marker Kit?
Order your kit online and once it arrive collect your sample at home.
Then, drop off the Kit in the morning to the Royal Mail Red Street Box. Use the Track24/48 Return Label to the Lab.
Lastly, once your results are ready, we will send you an email with your Result. Also you can view the report in your Dashboard.
1 BioMarker:
- CA125. Measures the level in your blood.
The marker is analysed through a blood sample taken in the morning before eating.
What type of CA125 results do I get?
The equipment gives the reference values, the working method and the reagents used, and these values may differ from one laboratory to another.
High levels
Levels are elevated in some cancers, including:
- uterine cervical;
- fallopian tube;
- pancreatic;
- breast;
- colorectal;
- lung;
- gastric, etc.
The results shows elevated levels in non-cancerous conditions, including:
- during menstruation;
- a task;
- endometriosis;
- any pelvic inflammatory disease;
- all non-cancerous ovarian cysts;
- most uterine fibroids, etc.
A decrease in the CA125 level during treatment usually means the disease responds to treatment. If the levels remain the same or increase during treatment, this may mean that the disease is not responding to treatment.
Diagnosis
The Ovarian marker helps diagnose and monitor various types of cancer. Therefore, it is also considered a secondary marker for lung, pancreatic, tubal, endometrial, and endocervical diseases.
And the analysis in treatment, prognosis assessment, and disease diagnosis. However, in the presence of a pelvic mass, it can distinguish between a benign process and a malignant condition.
An exam that is best in the following cases:
- if the doctor suspects that there is a disease in the body,
- to see if the treatment is working;
- and to see if it has recurred after treatment.
Also, certain situations and conditions besides ovarian disease that can cause levels to rise are:
- diverticulitis;
- endometriosis;
- uterine fibroids;
- inflammatory bowel disease;
- menstruation;
- liver diseases;
- pelvic inflammatory disease;
- peritonitis;
- task;
- recent surgical intervention;
- ruptured ovarian cyst.
Therefore, for someone with a family history, the doctor may recommend a Lab test to screen for it. Some doctors may recommend this exam combined with a transvaginal ultrasound every six months for those at very high risk.
But if you want to take a sample at one of the clinics near me.
Scientific Data from the CA125 Instrument and Reagent Supplier?
Technology Method:
Fluorescence quantitative immunoassay
Limit of Detection:
Less than or equal to 5.0 mIU/mL.
Accuracy and Precision:
The relative standard deviation from the target value is ≤ 15%. The within assay CV is ≤ 15%. The between assay CV is ≤ 15%.
Measuring Range:
Validation-Active Information:
- EQA: Yes
- Inter-laboratory validations
- Periodic according to validation schedule.
- Event-triggered- QC/Calibration/New materials/Batch
Accuracy and Precision:
The accuracy of these methods is based on the relative deviation. The relative deviation is the average deviation from the actual result value.
The precision relies on the within-assay coefficient of variations and the between-assay coefficient. The within-assay coefficient of variations is the variance of the result value if the same CA125 sample was analysed again. The between assay coefficient is the variance of the result value if the same sample was reprocessed from the beginning again.
In range results:
Healthy females are expected to have a value below 35 U/mL in the serum.
Out-of-range results:
Any value above 35 U/mL is considered abnormal. Those with elevated levels may be at risk.
Page Quality Review:
Review Date : 19/01/2024
Reviewed By :
A CA125 Tumour Story about Stacy
Stacey – Stage 4B – finished chemo 🙌
Finished my last round of weekly chemo, and my scans showed no visible signs of cancer. 🤯🎉
I’m moving on to Olaparib and would like to know if anyone has any advice. Also, do you have any thoughts on hair regrowth or skin improvements?
When I started this HPV journey, I read several older threads that I found very useful. Posting a few thoughts here in case someone else stumbles upon them in future years.
My experience: Going into chemo, I prepared for the worst, but it didn’t get difficult until the last couple of weeks. I could eat most foods, but for some reason mostly craved Indian food. Also, I saw several others in another cancer thread say the same thing. I used the ice gloves on my hands and feet. I never experienced neuropathy or numbness.
My hair didn’t fall out until about week 10
However, I shaved my head immediately. My hair didn’t completely fall out but got super sparse. I kept my eyelashes until week 18. Also, I got a port but wished I hadn’t. I think a port is good for most people; however, with me, it was terrible. I’m somewhat thin, so the port has a constant pain from not having body fat to cushion it. The port wound never healed and is still a wound that I have to manage. It sucks. There were several times the CA125 nurses didn’t want to use my port because of the wound and the bruising.
Don’t let the diagnosis steal your joy
Q&A for Stacey
Question: What About the Horrible pain and exhaustion?
Hi, I’d like to preface this by saying I made an appointment with my OBGYN today over these symptoms, and I haven’t been confirmed if I have ovarian cancer. My mom, a few nights ago, told me she had OC in the past and survived. And was concerned about my health recently and advised me to make this appointment.
I’ve been having HORRIBLE pain from my periods for years now, to the point where it’s hard for me to function; meditation doesn’t work anymore. It’s just severe pain. On top of that, I have recently been extremely exhausted from minor tasks, I feel like I’m starving, but I have no appetite; im losing weight rapidly, I don’t know what to do, I’m scared.
Answer:
Since OC isn’t detected on paps, make sure they check your ca-125 and do a CT scan. I’m sorry you’re in so much pain.
It’s completely natural to feel scared when facing such intense symptoms, especially given your mother’s history. Your decision to see an OBGYN is a vital step. While only a medical professional can give you answers, your symptoms — severe period pain, exhaustion, appetite changes, and weight loss — are signals that your body needs extra attention. Remember, many things can cause similar symptoms, and not all are as severe as cancer.
In the meantime, try to focus on small, manageable steps: get rest, drink fluids, and eat what you can, even if it’s just a little. If pain and anxiety get overwhelming, consider reaching out to a friend or family member to stay close by.
Lucy: A Question
Diagnosed with 3.5 cm ovarian endo, CEA and CA125 normal. Should I get a laparoscopy or watch and wait?
I have a 3-month follow-up U/S in 3 days since I opted for the watch-and-wait scenario rather than surgery since the OBGYN I dealt with told me she thinks the chance of cancer is low. Also, I told her my aunt died of OC, but that didn’t change her mind. I asked a couple of times to get the test but was told they wouldn’t do it because it doesn’t tell them anything, even when I asked to get it so I could know more when going in for my U/S and even just for my peace of mind.
So, I took matters into my own hands and bought a test through Ulta Labs. I went and got my blood drawn yesterday and got the results today. I got the CA125, CEA, and CBC, and everything was in the normal range. The CA125 was 18, so that makes me feel better.
So what would you do if you were in my shoes and the U/S shows no change in the endo? Keep monitoring it, or go in and have the lap done? I know the CA has shown up normal in people who ended up having cancer. I have no pain, and I wouldn’t even have known if this hadn’t been found as an incidental.
Answer: from Sylvia
Highly recommend having the laparoscopy. Some OC types do not secrete C 125. Mine didn’t. I was diagnosed with stage 3c. OC can go from stage 1 to 3 in a year. Don’t sit on it.
Lucy: What were your symptoms?
Sylvia: Initially, I had post-menopausal spotting, which triggered a gyne referral, endometrial biopsies and transvaginal ultrasound. Everything came back negative. Then, a year later had bloating and was very gassy. Checked for colon cancer with a colonoscopy, which was negative. I also felt a lump in my abdomen. CT was done and showed a large tumour. A biopsy was done, and a diagnosis of OC stage 3c was made.
Lucy: Oh, I am also gassy and had spotting for a month straight. The OB had me get an ultrasound, and she found polyps, which I am getting removed at the end of this month. I also Have pain on the right side of my stomach, pelvis and hip area. It gets extremely painful a couple of days before my period. Did you also have pain? How are you doing now?
I mean pain on my Left side only.
Sylvia: I didn’t have pain. Just before I started chemo, my abdomen was so swollen and hard it was super uncomfortable, but I wouldn’t call it pain. I’ve had chemo, surgery then finished chemo. Started on a PARP inhibitor for the last 4 months. I had a CT with contrast 2 weeks ago, and I will find out if it works tomorrow. It’s been a couple of anxiety-producing weeks.
Shipping and Return Policies
Appointment:
Missed appointments or cancellations less than 24 hours prior are not entitled to refunds. Rescheduling is possible but not guaranteed. Please contact the customer service prior to the appointment time to discuss cost and availability options.
Shipping & Return:
We have a 14-day return policy, which means you have 14 days after receiving your item to request a return.
To Qualify for any return, the product must be in the same condition as when you received it. Not used, not opened, unworn, in its original packaging. You will also need to send it to us with the receipt or proof of purchase.
Please return to: Medicines Online, 89 Falcon Rd, London. SW11 2PF
You can read our full return policy here:
https://medicinesonline.org.uk/return-policy/
We offer next day delivery; however courier delivery times are out of our control. We are unable to offer refunds for any late deliveries. But you will receive courier tracking information once your order has been dispatched. And orders placed by 1pm are dispatched on the same day.
CA125 Sales, Shipping & Return Policy?
We have a 14-day return policy, which means you have 14 days after receiving your item to request a return.
Therefore, to qualify for any return, the kit must be in the same condition as when you received it. However, it is not used, not opened, unworn, and in its original packaging. And remember, you must also send it to us with the receipt or proof of purchase.
Then, please return your kit to Medicines By Mailbox, 61 Falcon Rd, London. SW11 2PG.
You can read our full return policy here:
https://medicinesbymailbox.co.uk/return-policy/
We offer next-day delivery; however, courier delivery times are out of our control. We are unable to provide refunds for late deliveries. You will receive courier tracking information once your order has been dispatched. Orders placed by 1 p.m. are posted on the same day.
Liyla G. –
I was really impressed with the quick result turnaround time.
Princy Yolanda –
Our family has used them in the past for a few services and we had never had any complaints so far. Definitely recommend.
Polly F. –
Customer service was friendly and knowledgeable. Made the process easy for me!
Mila Rose –
The kit is easy to use
Viviane B. –
It went well, the product is simple to use
Catherine –
I had not understood the results, but after customer service helped me to clarify
Natalie –
Delivery was the very next day and the results were also quick
Bella –
Online Medicines is a fabulous company! I am very grateful to them
Melanie –
Thank you for the service. They were very supportive throughout the whole process