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• Myco Genotalia vs M. Pneumonia

What happened in France? A boom in cases: France.

While data on undiagnosed childhood pneumonia in China continues to be incomplete, a significant and abnormal increase in cases has also been recorded in recent weeks in other Asian countries, such as Vietnam, and in Europe, especially in France, where the infection has grown aggressively by 36% in children and young people under 15 years of age.

• France: alarm over the pneumonia bacterium

It is confirmed that the etiologically responsible agent of the cases across the Alps has been identified as pneumonia.

This known bacterium constantly mutates and is a common cause of community-acquired pneumonia (CAP).

According to infectious disease specialists, it is a widespread pathogen that has not circulated epidemically for 10 years. However, Experts are alarmed by the risks linked to antibiotic resistance, a global phenomenon that has worried the scientific community for years.

The antibiotic commonly used for this type of pneumonia – azithromycin, which is long-acting – is resistant worldwide, but no updated data on resistance rates are currently available. “Unfortunately, we do not have sufficient information to measure them due to the lack of circulation of the bacteria, especially after the Covid-19 pandemic,”

The Department of Infectious and Tropical Diseases of the Tenon Hospital in Paris announced in a statement.

The scientific community agrees that the increase in respiratory infections in children in various countries is caused by a post-pandemic immune gap, which exposes them to a greater risk of contracting common infections such as influenza and respiratory syncytial virus (RSV).

Since M. pneumonia seems only to affect children and does not affect the adult population, experts also believe that a new pathogen is not circulating. This is also confirmed by the scientific director of the Italian Society of Infectious and Tropical Diseases (SIMIT), Professor Massimo Andreoni, according to whom if we were faced with an unknown germ, there would be an evident increase in cases in every age group, because everyone would be equally immune as happened with Sars-CoV-2.

However, since it has been rather rare to identify real outbreaks.

Mycoplasma kits find some as pneumonia; pneumonia believes that the epidemic trend of these infections is due to a simultaneous circulation of other seasonal viruses, as confirmed by the Chinese authorities.

According to Francesco Vaia, the general director of health prevention at the Ministry of Health, Italy has no alarm. However, our country is expected to see an increase in cases of pneumonia and bronchiolitis in the coming weeks.
It is therefore necessary to continue careful surveillance using kits and consider that we can implement measures that can prevent pneumonia, such as using masks in the community, which are once again recommended in France.

The symptoms of pneumonia, both bacterial and viral, are flu-like and resemble those of Covid. Fever, cough, sore throat, and fatigue appear. In the case of M. Pneumonia, the cough is deep and persistent, and the breathing problems can even be serious.

After the acute infection, the bacterium persists airborne in a long asymptomatic phase that can last weeks and months. During this phase, it passes from person to person through direct contact and infected respiratory droplets. After exposure, incubation is approximately 23 days, and acquired immunity is short.

What does it mean when the spread of infection within the family is around 90%?

The therapy is specific to antibiotics that do not act on the bacterial wall since it is absent in the body. Macrolides, tetracyclines or fluoroquinolones are therefore used. But since many antibiotics cannot be administered in pediatric age, azithromycin, clarithromycin and doxycycline, all belonging to the category of macrolides, are preferably indicated.

However, resistance to macrolides has been found in all continents, sometimes with very high percentages, such as in China, where over 80% of subjects affected by this pneumonia do not respond to therapy.

Studies show that children affected by infections from strains resistant to macrolides present more severe and persistent symptoms than those infected by strains sensitive to these drugs. Doctors universally believe that adequate measures should be taken to curb such resistance.

Otherwise, it will lead to a very dangerous situation where no drugs will be available for pediatric patients.

Using other types of antibiotics also increases the likelihood that additional multi-resistant strains will emerge, making other common infections difficult or impossible to treat. Kits are the first step, says WHO. They have underlined that this significantly increases the risk of the general spread of infections, which, in the absence of adequate therapy, can lead to serious illnesses and even death. Some studies suggest that the treatment of Myco pneumonia could be oriented towards a short-acting macrolide, erythromycin, but the expected results require a long-term process.