Online prescriptions

  • Our doctors will review your order information and issue the prescription online direct to our pharmacy.

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Delivery to UK & EU

  • Our doctors will review your order information and issue the prescription online direct to our pharmacy.

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Acne treatment

Antibiotic or retinoid creams, gels and lotions, plus antibiotic tablets can be used to treat acne. Get these medicines on prescription from UK pharmacy.

Details

Dalacin T

Lymecycline

Zineryt lotion

Differin cream & gel

Isotrex gel

Epiduo gel

Medical information
Acne is common and can be potentially distressing. Fortunately, it is treatable.

Acne occurs mostly in teenagers between 12 to 25 years, but older people can also be affected. It commonly affects the face, but can also affect the back and chest areas.

We have small glands called sebaceous glands on our face that secrete oil (sebum) and we have tiny holes (pores) to allow oil to come to the surface. Acne arises when too much sebum is produced, possibly by hormonal change, forming a plug with dead skin cells which blocks the pores. These blocked pores are called comedones. They can form small spots which are known as papules. When the spots become inflamed with pus, they become pustules. Sometimes, discolouration (post-inflammatory hyperpigmentation) can remain on the skin a few months after the inflammation has gone, particularly on darker skin types.

There are many treatments available over the counter and through prescription, depending on severity. Used correctly, they can help clear up acne without scarring. Acne severity ranges from mild to severe. Mild and moderate form of acne can be treated by obtaining topical treatment (creams, gels, ointments or solutions) from chemists. However, severe form of acne usually needs prescription treatment, such as topical retinoid creams or gels and oral antibiotics, to prevent scarring. Prescription treatments can be obtained only through doctors, including online doctors.

Acne treatment from Medicinesbymailbox

Medicinesbymailbox does NOT supply medicines for under-18s.

Medicinesbymailbox is able to supply a range of prescription topical preparations (Differin, Isotrex, Zineryt, Dalacin T, Duac, and Epiduo) and antibiotic tablets (Lymecycline) for the treatment of acne.

Treatment is usually started from a lower dose topical preparation with a single active ingredient, then stepped up to topical preparation with more than one (dual) active ingredients. Antibiotic tablets may be prescribed with topical treatments for more persistent acne. See Acne treatment plans on this page.

Note: Not all treatments work well in all people. You may need to try different preparations to find the right one for you.

Some acne treatments are not available online from Medicinesbymailbox, particularly tretinoin tablets and Dianette.

Severe acne with scarring needs to be treated straightaway in face-to-face consultations with GPs or skin specialists.

Dalacin T, Zineryt, Differin, Isotrex, Duac, Epiduo, and Lymecycline 408mg are only available on prescription – our doctors will issue the prescription online direct to our pharmacy.

Ordering online

You must read the manufacturer's 'patient information leaflets' (links below) before ordering.

You will need to complete a short Yes/No questionnaire before ordering.

You should not usually use more than one topical treatment at the same time, without discussing this with a doctor. Sometimes, different topical preparations contain the same active ingredients. Some topical preparations may also contain two active ingredients.

Zineryt and Dalacin T – both antibiotics
Differin and Isotrex – both retinoids
Epiduo – retinoid with benzoyl peroxide
Duac – antibiotic with benzoyl peroxide
Oral antibiotic (lymecycline) can be used together with topical preparations without antibiotic such as Differin, Isotrex and Epiduo, but should NOT be taken whilst using Zineryt, Dalacin T and Duac.

Multiple ordering

After the consultation you can choose your order option, although it is not possible to order more than one item per consultation. This is for medical reasons.

If more than one item is required, a separate questionnaire must be completed for each item.

If more than one item has been ordered, you should web-message the doctors from your account to explain why.

If the doctors approve more than one item, email admin@medicinesbymailbox.com or web-message from your account and we will refund additional postage and consultation fees.

Declined orders are automatically refunded.

Diagnosis of acne

It is important that people obtaining treatment online for acne have previously seen a doctor about it. There are other causes of spots and rashes apart from acne, such as rosacea and psoriasis. These skin problems require further investigations, and might not respond to conventional acne treatment. Rarely, acne is associated with a disease in women called polycystic ovary syndrome. If you experience scalp hair loss, overgrowth of facial or body hair and irregular periods, you should be checked by your GP.

Length of treatment


It is important to carry out your treatment persistently. Treatment for acne takes time to work, usually at least 6 weeks and sometimes up to 4 months. Even if you feel that it is not working, it is best to carry on for at least 8 weeks before switching to, or adding a new one. If a treatment works well, stick with it. If there is no improvement or a worsening of acne after 8 weeks, a different treatment can be tried.



The best response to treatment is usually seen after 4 to 6 months. Treatment may be stopped after that if acne is very much improved, but may need to be restarted if it flares up again. It is common to have maintenance long-term treatment, usually at a lower amount than treatment dose. Topical antibiotics (Zineryt, Dalacin T, Duac) should not be used long term, as it may become less effective, due to resistance developed towards the antibiotics. Topical retinoid and benzoyl peroxide are usually used for maintenance teratment.

If your acne does not respond to traditional acne treatment and your acne is scarring, you should see a doctor straightaway.

Answer medical questions to order

You must read the important medical information for prescription tablets.

See medical information section

Have you read the acne important information page in full?

If you do not understand the medical information please do NOT order.
If more information is required, discuss with your own GP, or email, phone or message our doctors BEFORE ordering.

!

You must read the medical information. We are unable to supply acne medication for you.

  • Yes
  • No

Have you seen a doctor face-to-face and been diagnosed with acne?

Not including very minor illness that has completely resolved or occasional urinary infections.

!

You must see a doctor for a diagnosis before using online treatment. We are unable to supply acne treatment for you.

  • Yes
  • No

Have you read the manufacturer’s ‘patient information leaflet’ for the treatment you require?

See links to these leaflets on the medical information section. Read the leaflet(s) BEFORE ordering.

!

You must read the patient information leaflet before ordering. We are unable to supply acne medication for you.

  • Yes
  • No

Are you aware you should NOT USE more than one of the SAME TYPE of topical treatments at the SAME TIME?

  • Zineryt and Dalacin T - Both Antibiotics
  • Differin and Istorex - Both Retinoids
  • Epiduo - Antibiotic with Retinoid
  • Duac - Antibiotic with peeling agent (benzoyl peroxide)

!

You should NOT USE more than one of the SAME TYPE of topical treatments at the SAME TIME? You can change your answer and continue.

  • Yes
  • No

Are you aware Lymecycline antibiotic tablets should not be taken whilst using Zineryt, Dalacin T and Duac (topical antibiotics)?

Lymecycline can be taken whilst using Differin Istorex and Epiduo.

!

Lymecycline antibiotic tablets should not be taken whilst using Zineryt, Dalacin T and Duac (topical antibiotics). You can change your answer and continue.

PLEASE CONTINUE - doctors are likely to decline orders if Lymecycline is ordered at the same time as Zineryt, Dalacin T and Duac. Declined orders are automatically refunded.

  • Yes
  • No

Are you aware it usually takes 8 weeks or more of continuous usage for treatments to work?

If there is no improvement after 4 months, treatment should be stopped or changed.

!

It often takes 8 weeks or more for treatment to work. You can change your answer and continue.

  • Yes
  • No

Are you aware, if acne has cleared-up, treatment can sometimes be stopped or reduced after 4 to 6 months?

!

Acne treatment can sometimes be stopped or reduced after 4 to 6 months, if acne has cleared up. You can change your answer and continue.

  • Yes
  • No

Are you aware you should see your GP if acne is scarring or getting worse?

!

You should see your GP if acne is scarring or getting worse. You can change your answer and continue.

  • Yes
  • No

Are you allergic to the treatment you plan to order?

Zineryt (erythomycin), Dalacin T (clindamycin), Differin (adapalene), Isotrex (isotretinoin), Epiduo (adapalene with benzoyl peroxide), Duac (adapalene with clindamycin), Lymecycline (tetracycline).

!

We are unable to supply you with treatment. Please see your GP.

  • Yes
  • No

Are you aware the following treatments should NOT be used if you are pregnant or breast feeding?

  • Differin
  • Isotrex
  • Epiduo
  • Duac
  • Lymecycline
  • Details can be found in the ‘patient information leaflets’

!

Differin, Isotrex, Epiduo, Duac, Lymecycline should NOT we used or taken whilst pregnant or breast feeding. You can change your answer and continue.

  • Yes
  • No

Are you aware topical treatments containing retinoids and peeling agents (Differin, Isotrex, Epiduo and Duac) can be irritant?

Irritation can be reduced by starting treatment on alternate days, and building up to the prescribed dose as tolerated.

!

Topical treatments containing retinoids and peeling agents (Differin, Isotrex, Epiduo and Duac) can be irritant. Irritation can be reduced by starting treatment on alternate days, and building up to the prescribed dose as tolerated. You can change your answer and continue.

  • Yes
  • No

Are you ordering Lymecycline and been diagnosed with liver or kidney disease?

!

We are unable to supply you with treatment. Please see your GP.

  • Yes
  • No

Do the following apply to you?


  • I will read the information leaflet supplied with my pills
  • The contraception is for my own use
  • I am over 18
  • I agree to the terms and conditions


!

We are unable to provide prescription medication unless these conditions apply.

  • Yes
  • No

Prices

Acne treatment Pils Quantity Cost
Dalacin T topical lotion (clindamycin) 30mls £12.00
Dalacin T topical lotion (clindamycin)-1 45mls (1 x 60mls) £22.00
Dalacin T topical lotion (clindamycin)-3 90mls (3 x 30mls) £27.80
Dalacin T topical solution (clindamycin) 30mls £11.50
Dalacin T topical solution (clindamycin)- 60mls £16.00
Lymecycline 408mg 56 capsules £22.00
Lymecycline 408mg (antibiotic) 28-84 capsules £14.80
Lymecycline 408mg-2 84 capsules £32.00
Zineryt lotion (erythromycin in solution) 60mls (2 x 30mls) £25.00
Zineryt lotion (erythromycin in solution)-2 90mls (1 x 90mls) £33.00
Zineryt lotion (erythromycin) 30-90mls £14.20
Differin cream & gel (adapalene 0.1%) 45-90gms £22.00
Differin cream (adapalene 0.1%) 90 grams (2 x 45 grams) £39.00
Differin gel (adapalene 0.1%) 90 grams (2 x 45 grams) £39.00
Differin gel (adapalene 0.1%)-2 45 grams £22.00
Isotrex gel (isotretinoin 0.05%) 30 grams £14.80
Isotrex gel (isotretinoin 0.05%)-2 90 grams (3 x 30 grams) £36.00
Isotrex gel (isotretinoin 0.05%)-3 60 grams (2 x 30 grams) £26.00
Duac (benzoyl peroxide 3% & clindamycin 1%) 30gm tube £19.50
Duac Once Daily Gel (benzoyl peroxide 3% and clindamycin 1%) 60gm tube £35.80
Epiduo gel (benzoyl peroxide 2.5% & adapalene 0.1%) 45-135gms £26.20
Epiduo gel (benzoyl peroxide 2.5% and adapalene 0.1%) 90 grams (2 x 45 grams) £46.00
Epiduo gel (benzoyl peroxide 2.5% and adapalene 0.1%)- 135 grams (3 x 45 grams) £69.00
Medicinesbymailbox prices are 25%-50% lower cost than other online clinics.

Prescription fees

Medicinesbymailbox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.Prescriptions are issued by our doctors online and sent electronically to our pharmacy.If you have your own private paper prescription please post to our pharmacy (details).Medicinesbymailbox prices are 25%–50% lower than other UK online clinics.

Order value Prescription fee
Any Order Value £25.00
Items Medicinesbymailbox Dr. Fox Pharmacy2U Superdrug Express Pharmacy Lloyds Med Express
Dalacin T topical lotion (clindamycin) £12.00 £ 34.00 £ 23.00 £ 34.00 £ 22.99 £ 23.80 £ 24.00
Dalacin T topical lotion (clindamycin)-1 £22.00 £ 34.00 £ 35.00 £ 34.00 £ 35.00 £ 36.00 £ 37.00
Dalacin T topical lotion (clindamycin)-3 £27.80 £ 34.00 £ 334.99 £ 32.00 £ 31.55 £ 33.00 £ 34.00
Dalacin T topical solution (clindamycin) £11.50 £ 34.00 £ 17.00 £ 34.00 £ 16.99 £ 17.99 £ 18.99
Dalacin T topical solution (clindamycin)- £16.00 £ 34.00 £ 334.00 £ 34.00 £ 29.99 £ 334.20 £ 31.00
Lymecycline 408mg £22.00 £ 34.00 £ 22.99 £ 23.50 £ 24.00 £ 25.00 £ 25.99
Lymecycline 408mg (antibiotic) £14.80 £ 34.00 £ 15.00 £ 16.00 £ 16.99 £ 17.00 £ 18.00
Lymecycline 408mg-2 £32.00 £ 34.00 £ 32.99 £ 33.00 £ 33.80 £ 34.00 £ 35.00
Zineryt lotion (erythromycin in solution) £25.00 £ 34.00 £ 26.00 £ 26.99 £ 25.99 £ 27.00 £ 27.99
Zineryt lotion (erythromycin in solution)-2 £33.00 £ 34.00 £ 33.99 £ 34.00 £ 35.00 £ 35.99 £ 36.00
Zineryt lotion (erythromycin) £14.20 £ 34.00 £ 23.00 £ 22.50 £ 22.99 £ 32.55 £ 33.50
Differin cream & gel (adapalene 0.1%) £22.00 £ 34.00 £ 35.00 £ 34.00 £ 35.00 £ 35.99 £ 36.00
Differin cream (adapalene 0.1%) £39.00 NA NA NA NA NA NA
Differin gel (adapalene 0.1%) £39.00 £ 34.00 £ 434.00 £ 41.00 £ 42.00 £ 43.00 £ 44.00
Differin gel (adapalene 0.1%)-2 £22.00 £ 34.00 £ 23.00 £ 24.00 £ 25.00 £ 26.00 £ 27.00
Isotrex gel (isotretinoin 0.05%) £14.80 £ 34.00 £ 234.00 £ 34.00 £ 19.99 £ 22.00 £ 21.99
Isotrex gel (isotretinoin 0.05%)-2 £36.00 £ 34.00 £ 34.00 £ 35.00 £ 35.99 £ 36.00 £ 37.00
Isotrex gel (isotretinoin 0.05%)-3 £26.00 £ 34.00 £ 26.99 £ 26.80 £ 27.00 £ 28.00 £ 29.00
Duac (benzoyl peroxide 3% & clindamycin 1%) £19.50 £ 34.00 £ 234.00 £ 234.99 £ 21.50 £ 22.00 £ 23.00
Duac Once Daily Gel (benzoyl peroxide 3% and clindamycin 1%) £35.80 £ 34.00 £ 36.00 £ 36.99 £ 37.00 £ 37.99 £ 38.00
Epiduo gel (benzoyl peroxide 2.5% & adapalene 0.1%) £26.20 £ 34.00 £ 35.00 £ 49.00 £ 534.00 £ 534.99 £ 52.00
Epiduo gel (benzoyl peroxide 2.5% and adapalene 0.1%) £46.00 £ 34.00 £ 46.50 £ 46.99 £ 47.00 £ 47.80 £ 48.00
Epiduo gel (benzoyl peroxide 2.5% and adapalene 0.1%)- £69.00 £ 34.00 £ 69.99 £ 734.00 £ 72.00 £ 73.00 £ 74.00
*Medicinesbymailbox adds a small prescription fee not included in table above.

Delivery charges

UK delivery £2.90 per consultation via Royal Mail 24 Signed For (1-4 working days).

Standard international delivery £5.90 flat rate via Royal Mail International Tracked & Signed (2-5 working days).

Express international delivery £32.00 flat rate via DHL Express (2-8 days depending on destination, with tracking in transit).