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Colofac IBS tablets, containing an antispasmodic called mebeverine hydrochloride, are available from Medicinesbymailbox Pharmacy.

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Pills Quantity Cost
Colofac capsules m/r (mebeverine 200mg)-1 60 slow release capsules 1 twice daily tablets £11.3
Colofac capsules m/r (mebeverine 200mg)-2 120 slow release capsules 1 twice daily tablets £18.1
Colofac tablets (mebeverine 135mg) 100 tablets 1 three times daily tablets £12.1
Colofac tablets (mebeverine 135mg)- 200 tablets 1 three times daily tablets £21.4
Compare prices: Medicinesbymailbox prices are 25%-50% lower cost than other online clinics.

Prescription fees

Medicinesbymailbox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.Prescriptions are issued by our doctors online and sent electronically to our pharmacy.If you have your own private paper prescription please post to our pharmacy (details).Ascot Pharmacy prices are 25%–50% lower than other UK online clinics.

Order value Prescription fee
Any Order Value £25.00
Items Medicinesbymailbox Dr. Fox Pharmacy2U Superdrug Express Pharmacy Lloyds Med Express
Colofac capsules m/r (mebeverine 200mg)-1 £11.3 NA NA NA NA NA NA
Colofac capsules m/r (mebeverine 200mg)-2 £18.1 NA NA NA NA NA NA
Colofac tablets (mebeverine 135mg) £12.1 NA NA NA NA NA NA
Colofac tablets (mebeverine 135mg)- £21.4 NA NA NA NA NA NA
*Medicinesbymailbox adds a small prescription fee not included in table above.

Delivery charges

UK delivery £2.90 per consultation via Royal Mail 24 Signed For (1-4 working days).

Standard international delivery £5.90 flat rate via Royal Mail International Tracked & Signed (2-5 working days).

Express international delivery £32.00 flat rate via DHL Express (2-8 days depending on destination, with tracking in transit).

Colofac product information

Colofac IBS tablets contain Mebeverine hydrochloride which is classed as antispasmodics. It helps to relax stomach spasm and relieve cramps of the gut caused by IBS.

Along with taking Colofac, some simple lifestyle measures can also help to control symptoms of IBS. Please visit the condition medical information page.

How to take

The usual dose for IBS is to take one tablet 3 times daily. It should be taken 20 minutes before meal to help prevent symptoms appearing after meal. 

Side effects of Colofac

Like all medicines, Colofac can cause some side effects, although not everyone gets them.

Colofac can cause skin rash or itchy red skin. Side effects are usually mild but if you are concerned about any of these, you should speak to your doctor or pharmacist for more advice.

If you experience severe allergic reaction with symptoms such as difficulty breathing, swelling of the eyes, lips or face, you should stop taking Colofac and seek urgent medical advice.

For a full list of side effects, please refer to the patient information leaflet attached below.


When ordering from Medicinesbymailbox, you may be asked to fill in a series of yes/No questionnaire to determine your suitability to the medication. You should NOT take Colofac without consulting a doctor if:
  • You are allergic to mebeverine hydrochloride
  • you have not suffered from IBS before
  • you have liver or kidney problems
  • you have severe constipation
  • you have fever 
  • you are unusually pale or tired
  • you are pregnant or breastfeeding

Patient information leaflet

The 'patient information leaflet' supplied with the medication should be read before use.