Paludrine (proguanil 100mg)

Paludrine (proguanil), an anti-malarial medicine used to prevent malaria is available from the Medicinesbymailbox Pharmacy.

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Paludrine (proguanil 100mg)

Paludrine (proguanil 100mg)

Prescription fees

Medicinesbymailbox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.Prescriptions are issued by our doctors online and sent electronically to our pharmacy.If you have your own private paper prescription please post to our pharmacy (details).

Order value Prescription fee
Any Order Value £0.00

Paludrine product information

Paludrine contains an 'anti-malarial' medicine called proguanil. 
Malaria is caused by the bite of an infected mosquito which spreads the malaria parasite, P.falciparum. The active ingredient kills the parasites in the blood. Paludrine is used to prevent malaria.

Note: no anti-malarial tablet is 100% effective against malaria and you may need additional measures to prevent getting bitten by infected mosquitoes. Visit our page for malaria for specific medical information.

How to take

You may need to start taking the tablets for a specific time period before and after entering malaria risk areas. Always take this medicine exactly as your doctor or pharmacist tells you to. The usual dose for malaria prevention is to take two paludrine tablets once daily, preferably at the same time each day. You should start taking the tablets a week before entering malarial areas and continue with this medicine throughout until 4 weeks after leaving the area. It is important to finish the whole course of medicine to gain adequate protection.
It is preferable to take this medicine after food and swallow the tablets with a drink of water. 

Side effects of Paludrine

Like all medicines, proguanil can cause some side effects, although not everyone gets them.
Some common side effects include stomach upset such as diarrhoea, constipation and sore mouth or ulcers. 
For a full list of side effects, please refer to the patient information leaflet attached below.
If you notice severe allergic reaction with symptoms such as rash and itching, swollen eyes, face or lips and difficulty breathing, you should stop taking the combination pack and seek medical advice immediately.


During a Medicinesbymailbox online consultation, you will be required to complete an assessment questionnaire to determine your suitability for anti-malarial medication. You should not take Malarone without consulting a doctor if you:
  • Are allergic to proguanil
  • Have kidney disease

You are advised to speak to a doctor or pharmacist before taking the tablets if you are pregnant or breast feeding.

Some medicines can also interfere with how the medication works, for example a blood thinning medicine called Warfarin. If you are unsure, you should check with a doctor or pharmacist for advice.

Some indigestion remedies might affect absorption of Paludrine so they should not be taken at least two hours before and after Paludrine is administered.

Medicinesbymailbox can only prescribe medicine to adults (18 years or over). 

Patient information leaflet – Malarone

The 'Patient Information Leaflets' supplied with medication must be read before taking tablets.