Lymecycline 408mg antibiotic (tetracycline) capsules can be prescribe by Medicinesbymailbox online doctor to treat acne.

0 reviews


Prescription fees

Medicinesbymailbox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.Prescriptions are issued by our doctors online and sent electronically to our pharmacy.If you have your own private paper prescription please post to our pharmacy (details).

Order value Prescription fee
Any Order Value £0.00

Lymecycline capsules product information

Lymecycline belongs to a group of antibiotics called tetracyclines. 

Acne is associated with the growth of bacteria called propionibacterium in the clogged pores on our skin. Lymecycline and other antibiotic treatments, reduce the number of these bacteria and reduce the inflammation. 

How to take

Lymecycline 480mg capsules are taken once daily for the treatment of acne and should be taken with a glass of water, preferably in the morning. It should not be taken 2 hours before or after some medicines, particularly indigestion tablets, ulcer healing drugs or supplements containing aluminium, calcium, magnesium, zinc or iron - see the manufacturer’s patient information leaflet for more details.

Treatment duration

Like other acne treatments, Lymecycline is best used regularly. It can take at least 8 weeks of treatment before acne improves. Treatment should be tried continuously for at least 8 weeks. If after 8 weeks, there is no improvement, a different treatment should be tried.

Lymecycline can be used long-term, although in some cases it will become less effective after prolonged use due to resistance developed towards the antibiotic.

It is not recommended to use more than one antibiotic at the same time, unless advised by doctor. One antibiotic should be stopped before the next one is tried.

If acne has resolved after 4-6 months, treatment can be reduced or stopped. In many cases acne will not come back. Treatments may need to be restarted if acne returns.

Side effects of Lymecycline 

Like any medicine, Lymecycline can cause side effects although not everyone gets them. It does not always indicate that treatment should be stopped. Heartburn and indigestion, nausea and diarrhoea are common side effects of this medicine. If this becomes a concern to you, speak to a doctor or pharmacist for advice. Some people also develop thrush (redness and itchiness in the mouth or vagina) after taking antibiotics. If this happens, speak to a doctor or pharmacist for advice.

If you experience symptoms such as facial swelling, difficulty breathing, peeling and blistering of the skin, seek emergency treatment as it might be a sign of allergic reaction. It is uncommon and usually occurs at the beginning of treatment.

Lymecycline, like other tetracyclines, can increase sensitivity to sunlight, exposure to sun should be reduced or avoided while on this medicine. Use of sunscreen with a high sun protection factor is encouraged.


It is not for use in children under 12 years, and is only available from Medicinesbymailbox to over 18s.

Pregnant and breast-feeding women must NOT take Lymecycline. It is also not suitable for people with a medical history of liver or kidney disease, a long term condition called systemic lupus erythematosus (known as 'lupus') or a muscle condition called Myasthenia Gravis. If you have these diseases, you should consult your doctor before taking these medicines.

Lymecycline should not be taken with other antibiotics or whilst using topical acne treatments containing antibiotics e.g. ZinerytDalacin T and Duac, unless advised by doctor.

Other acne treatments

Where topical treatments are effective, switching to oral antibiotics should not be necessary. Oral antibiotics, such as Lymecycline, may be more effective than topical antibiotic acne treatments for more persistent acne.

Minocycline is an alternative type of tetracycline antibiotic used to treat acne, but it is not suggested to be used due to higher risk of side effects. Macrolide antibiotic, such as erythromycin, are sometimes prescribed as an alternative to tetracyclines, but is not always helpful for acne.

Topical peeling and anti-inflammatory preparations can be used with Lymecycline treatment e.g benzoyl peroxide, Isotrex and Epiduo. They work differently from antibiotics and may be beneficial if treatment with antibiotic alone is not enough to control acne.

A range of acne treatments are available at Medicinesbymailbox Pharmacy.

Patient information leaflet – Lymecycline

The 'Lymecycline patient information leaflet' supplied with medication must be read before use.