Lariam (mefloquine 250mg) is a prescription only medicine. It is available from Medicinesbymailbox Pharmacy, along with other anti-malarial medications for the prevention of malaria.

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Prescription fees

Medicinesbymailbox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.Prescriptions are issued by our doctors online and sent electronically to our pharmacy.If you have your own private paper prescription please post to our pharmacy (details).

Order value Prescription fee
Any Order Value £0.00

Lariam product information

Lariam is a medicine which contains 250mg of an active ingredient called mefloquine. Malaria is caused by the bite of an infected mosquito which spreads the malaria parasite, P.falciparum. Lariam stops the growth of the parasite in blood and helps prevent you from catching malaria. 

Note: no anti-malarial tablet is 100% effective against malaria and you may need additional measures to prevent getting bitten by infected mosquitoes. Visit our page for malaria for specific medical information.

How to take

You must take the tablets exactly as your doctor tells you to. The typical dose to prevent malaria is to take one Lariam tablet on the same day each week, starting 10 days before entering malarial areas. Continue with the tablets weekly whilst at malarial areas until 4 weeks after leaving the area. The minimum course of treatment should be 6 weeks, depending the duration of your stay in malaria risk areas. It is important to finish the whole course of treatment to ensure adequate protection.

Swallow the tablets with plenty of water and preferably after food.

Side effects of Lariam

Like all medicines, Lariam can cause some side effects, although not everyone gets them.

Common side effects of Lariam include depression and anxiety. It is important that if you experience any of these symptoms that you stop taking the tablets and contact your doctor immediately. This is because Lariam may cause some serious mental health problems in some people. 

Other common side effects of Lariam are sleeping problems, dizziness, headache and problems with your vision. If Lariam does affect your vision, care should be taken whilst driving or operating machinery.

Although it is uncommon, if you notice severe allergic reaction with symptoms such as rash and itching, swollen eyes, face or lips and difficulty breathing, you should stop taking Lariam and seek medical advice immediately.

The full list of side effects can be found in the patient information leaflet attached below.


During a Medicinesbymailbox online consultation, you will be required to complete an assessment questionnaire to determine your suitability for anti-malarial medication. You should not take Lariam without consulting a doctor if you:
  • Are allergic to mefloquine
  • Are pregnant or breast-feeding
  • Have conditions such as suicidal thoughts, depression and any other mental health problems
  • Have or have had fits or seizures
  • Have severe liver problems

Some medicines can also interfere with how Malarone works, for example some medications for high blood pressure or other heart problems, antihistamines for allergies and some antidepressants. If you are unsure, you should check with a doctor or pharmacist for advice.

Medicinesbymailbox can only prescribe medicine to adults (18 years or over). 

Patient information leaflet – Lariam

The 'Patient Information Leaflets' supplied with medication must be read before taking tablets.