Colofac IBS tablets, containing an antispasmodic called mebeverine hydrochloride, are available from Medicinesbymailbox Pharmacy.

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Prescription fees

Medicinesbymailbox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.Prescriptions are issued by our doctors online and sent electronically to our pharmacy.If you have your own private paper prescription please post to our pharmacy (details).

Order value Prescription fee
Any Order Value £0.00

Colofac product information

Colofac IBS tablets contain Mebeverine hydrochloride which is classed as antispasmodics. It helps to relax stomach spasm and relieve cramps of the gut caused by IBS.

Along with taking Colofac, some simple lifestyle measures can also help to control symptoms of IBS. Please visit the condition medical information page.

How to take

The usual dose for IBS is to take one tablet 3 times daily. It should be taken 20 minutes before meal to help prevent symptoms appearing after meal. 

Side effects of Colofac

Like all medicines, Colofac can cause some side effects, although not everyone gets them.

Colofac can cause skin rash or itchy red skin. Side effects are usually mild but if you are concerned about any of these, you should speak to your doctor or pharmacist for more advice.

If you experience severe allergic reaction with symptoms such as difficulty breathing, swelling of the eyes, lips or face, you should stop taking Colofac and seek urgent medical advice.

For a full list of side effects, please refer to the patient information leaflet attached below.


When ordering from Medicinesbymailbox, you may be asked to fill in a series of yes/No questionnaire to determine your suitability to the medication. You should NOT take Colofac without consulting a doctor if:
  • You are allergic to mebeverine hydrochloride
  • you have not suffered from IBS before
  • you have liver or kidney problems
  • you have severe constipation
  • you have fever 
  • you are unusually pale or tired
  • you are pregnant or breastfeeding

Patient information leaflet

The 'patient information leaflet' supplied with the medication should be read before use.